Spermatogenesis associated 13
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| SPATA13 |
|---|
|
| Identifiers |
|---|
Aliases |
SPATA13, ARHGEF29, ASEF2, spermatogenesis associated 13 |
|---|
External IDs |
MGI: 104838 HomoloGene: 19482 GeneCards: SPATA13 |
|---|
| Gene location (Mouse) |
|---|
 |
Chr. |
Chromosome 14 (mouse)[1] |
|---|
|
Band |
14 D1|14 31.77 cM |
Start |
60,634,001 bp[1] |
|---|
End |
60,764,556 bp[1] |
|---|
|
| Gene ontology |
|---|
Molecular function |
• Rac guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor activity • protein binding • guanyl-nucleotide exchange factor activity • identical protein binding
|
|---|
Cellular component |
• cytoplasm • filopodium • ruffle membrane • plasma membrane • cell projection • membrane • lamellipodium • nucleoplasm • cytosol
|
|---|
Biological process |
• filopodium assembly • regulation of Rho protein signal transduction • regulation of cell migration • cell migration • lamellipodium assembly
|
|---|
Sources:Amigo / QuickGO
|
|
| Orthologs |
|---|
Species |
Human |
Mouse |
|---|
Entrez |
|
|
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Ensembl |
|
|
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UniProt |
|
|
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RefSeq (mRNA) |
NM_001166271 NM_001286792 NM_001286793 NM_001286794 NM_001286795
|
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NM_153023 |
|
|
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RefSeq (protein) |
NP_001159743 NP_001273721 NP_001273722 NP_001273723 NP_001273724
|
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NP_694568 NP_694568.1 |
|
|
|---|
Location (UCSC) |
n/a |
Chr 14: 60.63 – 60.76 Mb |
|---|
PubMed search |
[2] |
[3] |
|---|
| Wikidata |
View/Edit Human |
View/Edit Mouse |
|
Spermatogenesis associated 13 is a protein that in humans is encoded by the SPATA13 gene.
[4]
References[edit]
^ abc GRCm38: Ensembl release 89: ENSMUSG00000021990 - Ensembl, May 2017
^ "Human PubMed Reference:"..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"""""""'""'"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
^ "Mouse PubMed Reference:".
^
"Entrez Gene: Spermatogenesis associated 13". Retrieved 2018-04-26.
Further reading[edit]
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Kawasaki Y, Sagara M, Shibata Y, Shirouzu M, Yokoyama S, Akiyama T (December 2007). "Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42". Oncogene. 26 (55): 7620–267. doi:10.1038/sj.onc.1210574. PMID 17599059.
Sagara M, Kawasaki Y, Iemura SI, Natsume T, Takai Y, Akiyama T (March 2009). "Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration". Oncogene. 28 (10): 1357–65. doi:10.1038/onc.2008.478. PMID 19151759.
Ding H, Xu Y, Bao X, Wang X, Cui G, Wang W, Hui R, Wang DW (January 2010). "Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke". Stroke. 41 (1): 177–80. doi:10.1161/STROKEAHA.109.567099. PMID 19910543.
Bristow JM, Sellers MH, Majumdar D, Anderson B, Hu L, Webb DJ (December 2009). "The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration". J. Cell Sci. 122 (Pt 24): 4535–46. doi:10.1242/jcs.053728. PMC 2787464. PMID 19934221.
Jean L, Majumdar D, Shi M, Hinkle LE, Diggins NL, Ao M, Broussard JA, Evans JC, Choma DP, Webb DJ (December 2013). "Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen". J. Cell Sci. 126 (Pt 24): 5585–97. doi:10.1242/jcs.131060. PMC 3860307. PMID 24144700.
Categories:
- Genes on human chromosome
- Human chromosome 13 gene stubs
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